TAIL MELANOPHORES OF XENOPUS IN NORMAL DEVELOPMENT AND REGENERATION
نویسندگان
چکیده
منابع مشابه
Tadpole tail regeneration in Xenopus.
Some organisms have a remarkable ability to heal wounds without scars and to regenerate complex tissues following injury. By gaining a more complete understanding of the biological mechanisms that promote scar-free healing and tissue regeneration, it is hoped that novel treatments that can enhance the healing and regenerative capacity of human patients can be found. In the present article, we b...
متن کاملTail regeneration in the Xenopus tadpole.
The tail of the Xenopus tadpole contains major axial structures, including a spinal cord, notochord and myotomes, and regenerates within 2 weeks following amputation. The tail regeneration in Xenopus can provide insights into the molecular basis of the regeneration mechanism. The regenerated tail has some differences from the normal tail, including an immature spinal cord and incomplete segment...
متن کاملCell lineage tracing during Xenopus tail regeneration.
The tail of the Xenopus tadpole will regenerate following amputation, and all three of the main axial structures - the spinal cord, the notochord and the segmented myotomes - are found in the regenerated tail. We have investigated the cellular origin of each of these three tissue types during regeneration. We produced Xenopus laevis embryos transgenic for the CMV (Simian Cytomegalovirus) promot...
متن کاملTagging muscle cell lineages in development and tail regeneration using Cre recombinase in transgenic Xenopus.
The use of Cre and FLP recombinases to analyze embryogenesis and organogenesis in Xenopus has not been applied so far. We report on the generation of transgenic Xenopus animals containing a Cre-activated reporter gene cassette expressing blue fluorescent protein that can be switched over to yellow fluorescent protein expression upon Cre-mediated recombination. By injecting Cre mRNA into the two...
متن کاملEarly requirement of Hyaluronan for tail regeneration in Xenopus tadpoles.
Tail regeneration in Xenopus tadpoles is a favorable model system to understand the molecular and cellular basis of tissue regeneration. Although turnover of the extracellular matrix (ECM) is a key event during tissue injury and repair, no functional studies to evaluate its role in appendage regeneration have been performed. Studying the role of Hyaluronan (HA), an ECM component, is particularl...
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ژورنال
عنوان ژورنال: The Biological Bulletin
سال: 1960
ISSN: 0006-3185,1939-8697
DOI: 10.2307/1539050